When taken for its fat-loss properties, Clenbuterol, is best used in a pyramid scheme. This means slowly building up the dose over time. Given its effects on blood pressure it’s best to start with 20-40 mcg per day and slowly work up to a maximum of 120-160 mcg per day. Most bodybuilders find that 80 mcg is the best compromise in terms of positive and negative effects. Its also best not to use the drug for extended periods of time. In fact because of receptor desensitizing, clen seems to only cause fat loss for three to four weeks. To get around this most bodybuilders go off the drug for two to three weeks and then begin another three to four week cycle.